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Grupo de investigación

GC04 GC04 Inflamación y cáncer

Publicaciones 2023

Blázquez-Encinas R, García-Vioque V, Caro-Cuenca T, Moreno-Montilla MT, Mangili F, Alors-Pérez E, Ventura S, Herrera-Martínez AD, Moreno-Casado P, Calzado MA, Salvatierra A, Gálvez-Moreno MA, Fernandez-Cuesta L, Foll M, Luque RM, Alcala N, Pedraza-Arevalo S, Ibáñez-Costa A, Castaño JP

Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery

JOURNAL OF TRANSLATIONAL MEDICINE

DOI: 10.1186/s12967-023-04754-8

Publicaciones 2023

Jimenez-Izquierdo R, Morrugares R, Suanes-Cobos L, Correa-Saez A, Garrido-Rodriguez M, Cerero-Tejero L, Khan OM, de la Luna S, Sancho R, Calzado MA

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2

CELL DEATH & DISEASE

DOI: 10.1038/s41419-023-05724-0

Publicaciones 2023

Lavayen BP, Yang CJ, Larochelle J, Liu L, Tishko RJ, de Oliveira ACP, Munoz E, Candelario-Jalil E

Neuroprotection by the cannabidiol aminoquinone VCE-004

8 in experimental ischemic stroke in mice

DOI: 10.1016/j.neuint.2023.105508

Publicaciones 2023

Silva L, Vargas C, Prados ME, Del Pozo A, Villa M, Martinez M, Alvarez L, Munoz E, Unciti-Broceta JD, Martinez-Orgado J

Neuroprotective Efficacy of Betulinic Acid Hydroxamate, a B55 alpha/PP2A Activator, in Acute Hypoxia-Ischemia-Induced Brain Damage in Newborn Rats

TRANSLATIONAL STROKE RESEARCH

DOI: 10.1007/s12975-022-01017-4

Publicaciones 2023

Rodríguez-Carreiro S, Navarro E, Muñoz E, Fernández-Ruiz J

The Cannabigerol Derivative VCE-003

2 Exerts Therapeutic Effects in 6-Hydroxydopamine-Lesioned Mice: Comparison with The Classic Dopaminergic Replacement Therapy

DOI: 10.3390/brainsci13091272

Publicaciones 2023

Maier CR, Hartmann O, Prieto-Garcia C, Al-Shami KM, Schlicker L, Vogel FCE, Haid S, Klann K, Buck V, Muench C, Schmitz W, Einig E, Krenz B, Calzado MA, Eilers M, Popov N, Rosenfeldt MT, Diefenbacher ME, Schulze A

USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer

CELL DEATH AND DIFFERENTIATION

DOI: 10.1038/s41418-023-01173-6

Publicaciones 2023

Prados ME, Navarrete C, Garcia-Martin A, Lastres-Cubillo I, Ponce-Diaz F, Martinez-Orgado J, Munoz E

VCE-005

1, an hypoxia mimetic betulinic acid derivative, induces angiogenesis and shows efficacy in a murine model of traumatic brain injury

DOI: 10.1016/j.biopha.2023.114715

Publicaciones 2022

Navarrete C, Garcia-Martin A, Correa-Saez A, Prados ME, Fernandez F, Pineda R, Mazzone M, Alvarez-Benito M, Calzado MA, Munoz E

JOURNAL OF NEUROINFLAMMATION

2022

DOI: 10.1186/s12974-022-02540-9

Publicaciones 2022

Lara-Chica M, Correa-Saez A, Jimenez-Izquierdo R, Garrido-Rodriguez M, Ponce FJ, Moreno R, Morrison K, Di Vona C, Arato K, Jimenez-Jimenez C, Morrugares R, Schmitz ML, de la Luna S, de la Vega L, Calzado MA

CELL DEATH AND DIFFERENTIATION

2022

DOI: 10.1038/s41418-021-00845-5

Publicaciones 2022

Chianese G, Sirignano C, Benetti E, Marzaroli V, Collado JA, de la Vega L, Appendino G, Munoz E, Taglialatela-Scafati O

JOURNAL OF NATURAL PRODUCTS

2022

DOI: 10.1021/acs.jnatprod.1c01198

Publicaciones 2022

Appendino G, Taglialatela-Scafati O, Munoz E

NATURAL PRODUCT COMMUNICATIONS

2022

DOI: 10.1177/1934578X221098843

Publicaciones 2022

del Rio C, Ruiz-Pino F, Prados ME, Fiebich BL, Tena-Sempere M, Munoz E

FRONTIERS IN PHARMACOLOGY

2022

DOI: 10.3389/fphar.2022.981817

Publicaciones 2022

Apweiler M, Streyczek J, Saliba SW, Collado JA, Hurrle T, Grassle S, Munoz E, Normann C, Hellwig S, Brase S, Fiebich BL

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2022

DOI: 10.3390/ijms23020959

Publicaciones 2022

Caprioglio D, Amin HIM, Taglialatela-Scafati O, Munoz E, Appendino G

BIOMOLECULES

2022

DOI: 10.3390/biom12081084

Publicaciones 2022

Del Pozo A, Silva L, Romero A, De Hoz-Rivera M, Villa M, Martinez-Vega M, Prados ME, Munoz E, Martinez-Orgado J

NUTRIENTS

2022

DOI: 10.3390/nu14245286

Publicaciones 2022

Caprioglio D, Mattoteia D, Munoz E, Taglialatela-Scafati O, Appendino G

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

2022

DOI: 10.1002/ejoc.202101410

Publicaciones 2022

Rao ZG, Caprioglio D, Gollowitzer A, Kretzer C, Imperio D, Collado JA, Waltl L, Lackner S, Appendino G, Munoz E, Temml V, Werz O, Minassi A, Koeberle A

BIOCHEMICAL PHARMACOLOGY

2022

DOI: 10.1016/j.bcp.2022.115202

Publicaciones 2022

Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Bozkurt S, Pahor N, Fuss C, Schirbel A, Schulein-Volk C, Buchberger A, Canale MAC, Rosenfeldt M, Dikic I, Munch C, Diefenbacher ME

MOLECULAR ONCOLOGY

2022

DOI: 10.1002/1878-0261.13217

Publicaciones 2021

Gonzalez-Mariscal I, Carmona-Hidalgo B, Winkler M, Unciti-Broceta JD, Escamilla A, Gomez-Canas M, Fernandez-Ruiz J, Fiebich BL, Romero-Zerbo SY, Bermudez-Silva FJ, Collado JA, Munoz E

(+)-trans-Cannabidiol-2-hydroxy pentyl is a dual CB1R antagonist/CB2R agonist that prevents diabetic nephropathy in mice

PHARMACOLOGICAL RESEARCH

DOI: 10.1016/j.phrs.202105492

Publicaciones 2021

Salamone S, Appendino G, Khalili A, Pollastro F, Munoz E, Unciti-Broceta JD

Agathadiol, a labdane diterpenoid from juniper berries, is a positive allosteric modulator of CB1R

FITOTERAPIA

DOI: 10.1016/j.fitote.2021.105059

Publicaciones 2021

IF: 2,882 Q3

Publicaciones 2021

Prados ME, Correa-Saez A, Unciti-Broceta JD, Garrido-Rodriguez M, Jimenez-Jimenez C, Mazzone M, Minassi A, Appendino G, Calzado MA, Munoz E

Betulinic Acid Hydroxamate is Neuroprotective and Induces Protein Phosphatase 2A-Dependent HIF-1 alpha Stabilization and Post-transcriptional Dephosphorylation of Prolyl Hydrolase 2

NEUROTHERAPEUTICS

DOI: 10.1007/s13311-021-01089-4

Publicaciones 2021

Prados ME, Garcia-Martin A, Unciti-Broceta JD, Palomares B, Collado JA, Minassi A, Calzado MA, Appendino G, Munoz E

Betulinic acid hydroxamate prevents colonic inflammation and fibrosis in murine models of inflammatory bowel disease

ACTA PHARMACOLOGICA SINICA

DOI: 10.1038/s41401-020-0497-0

Publicaciones 2021

Navarrete C, Garcia-Martin A, Rolland A, DeMesa J, Munoz E

Cannabidiol and Other Cannabinoids in Demyelinating Diseases

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DOI: 10.3390/ijms22062992

Publicaciones 2021

IF: 5,923 Q1 D3

Publicaciones 2021

Caprioglio D, Mattoteia D, Taglialatela-Scafati O, Munoz E, Appendino G

Cannabinoquinones: Synthesis and Biological Profile

BIOMOLECULES

DOI: 10.3390/biom11070991

Publicaciones 2021

IF: 4,879 Q2 D4

Publicaciones 2021

Carmona-Hidalgo B, Gonzalez-Mariscal I, Garcia-Martin A, Prados ME, Ruiz-Pino F, Appendino G, Tena-Sempere M, Munoz E

Delta 9-Tetrahydrocannabinolic Acid markedly alleviates liver fibrosis and inflammation in mice

PHYTOMEDICINE

DOI: 10.1016/j.phymed.2020.153426

Publicaciones 2021

IF: 5,34 Q1 D1

Publicaciones 2021

Carmona-Hidalgo B, Garcia-Martin A, Munoz E, Gonzalez-Mariscal I

Detrimental Effect of Cannabidiol on the Early Onset of Diabetic Nephropathy in Male Mice

PHARMACEUTICALS

DOI: 10.3390/ph14090863

Publicaciones 2021

IF: 5,863 Q1 D2

Publicaciones 2021

Garcia-Martin A, Navarrete C, Garrido-Rodriguez M, Prados ME, Caprioglio D, Appendino G, Munoz E

EHP-101 alleviates angiotensin II-induced fibrosis and inflammation in mice

BIOMEDICINE & PHARMACOTHERAPY

DOI: 10.1016/j.biopha.2021.11200

Publicaciones 2021

IF: 6,529 Q1 D1

Publicaciones 2021

Garrido-Rodriguez M, Lopez-Lopez D, Ortuno FM, Pena-Chilet M, Munoz E, Calzado MA, Dopazo J

A versatile workflow to integrate RNA-seq genomic and transcriptomic data into mechanistic models of signaling pathways

PLOS COMPUTATIONAL BIOLOGY

DOI: 10.1371/journal.pcbi.1008748

Publicaciones 2021

IF: 4,475 Q1 D2

Publicaciones 2021

Apweiler M, Streyczek J, Saliba SW, Ditrich J, Munoz E, Fiebich BL

Anti-Inflammatory and Anti-Oxidative Effects of AM404 in IL-1 beta-Stimulated SK-N-SH Neuroblastoma Cells

FRONTIERS IN PHARMACOLOGY

DOI: 10.3389/fphar.2021.789074

Publicaciones 2021

Hartmann O, Reissland M, Maier CR, Fischer T, Prieto-Garcia C, Baluapuri A, Schwarz J, Schmitz W, Garrido-Rodriguez M, Pahor N, Davies CC, Bassermann F, Orian A, Wolf E, Schulze A, Calzado MA, Rosenfeldt MT, Diefenbacher ME

Implementation of CRISPR/Cas9 Genome Editing to Generate Murine Lung Cancer Models That Depict the Mutational Landscape of Human Disease

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY

DOI: 10.3389/fcell.2021.641618

Publicaciones 2021

IF: 6,684 Q1 D2

Publicaciones 2021

Burgaz S, Garcia C, Gomez-Canas M, Rolland A, Munoz E, Fernandez-Ruiz J

Neuroprotection with the Cannabidiol Quinone Derivative VCE-008 (EHP-101) against 6-Hydroxydopamine in Cell and Murine Models of Parkinson's Disease

MOLECULES

DOI: 10.3390/molecules26113245

Publicaciones 2021

IF: 4,411 Q2 D4

Publicaciones 2021

Burgaz S, Garcia C, Gomez-Canas M, Navarrete C, Garcia-Martin A, Rolland A, del Rio C, Casarejos MJ, Munoz E, Gonzalo-Consuegra C, Munoz E, Fernandez-Ruiz J

Neuroprotection with the cannabigerol quinone derivative VCE-003

2 and its analogs CBGA-Q and CBGA-Q-Salt in Parkinson's disease using 6-hydroxydopamine-lesioned mice

DOI: 10.1016/j.mcn.2020.103583

Publicaciones 2021

IF: 4,314 Q2 D4

Publicaciones 2021

Rodriguez-Soacha DA, Fender J, Ramirez YA, Collado JA, Munoz E, Maitra R, Sotriffer C, Lorenz K, Decker M

Photo-Rimonabant: Synthesis and Biological Evaluation of Novel Photoswitchable Molecules Derived from Rimonabant Lead to a Highly Selective and Nanomolar "Cis-On" CB1R Antagonist

ACS CHEMICAL NEUROSCIENCE

DOI: 10.1021/acschemneuro.1c0008

Publicaciones 2021

IF: 4,418 Q2 D3

Publicaciones 2021

Fallas MEA, Pedraza-Arevalo S, Cujba AM, Manea T, Lambert C, Morrugares R, Sancho R

Stem/progenitor cells in normal physiology and disease of the pancreas

MOLECULAR AND CELLULAR ENDOCRINOLOGY

DOI: 10.1016/j.mce.2021.111459

Publicaciones 2020

Flores-Giubi ME, Botubol-Ares JM, Duran-Pena MJ, Escobar-Montano F, Zorrilla D, Sanchez-Marquez J, Munoz E, Macias-Sanchez AJ, Hernandez-Galan R

Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone

PHYTOCHEMISTRY

DOI: 10.1016/j.phytochem.2020.112519

Publicaciones 2020

IF: 3,044 Q: 1

Publicaciones 2020

Casares L, Garcia V, Garrido-Rodriguez M, Millan E, Collado JA, Garcia-Martin A, Penarando J, Calzado MA, de la Vega L, Munoz E

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

REDOX BIOLOGY

DOI: 10.1016/j.redox.2019.101321

Publicaciones 2020

IF: 9,986 Q: 1 D: 1

Publicaciones 2020

Navarrete C, Garcia-Martin A, DeMesa J, Munoz E

Cannabinoids in Metabolic Syndrome and Cardiac Fibrosis

CURRENT HYPERTENSION REPORTS

DOI: 10.1007/s11906-020-01112-7

Publicaciones 2020

IF: 3,856 Q: 2

Publicaciones 2020

Palomares B, Garrido-Rodriguez M, Gonzalo-Consuegra C, Gomez-Canas M, Saen-oon S, Soliva R, Collado JA, Fernandez-Ruiz J, Morello G, Calzado MA, Appendino G, Munoz E

Delta(9)-Tetrahydrocannabinolic acid alleviates collagen-induced arthritis: Role of PPAR gamma and CB(1)receptors

BRITISH JOURNAL OF PHARMACOLOGY

DOI: 10.1111/bph.15155

Publicaciones 2020

IF: 7,73 Q: 1 D: 1

Publicaciones 2020

Navarrete C, Garcia-Martin A, Garrido-Rodriguez M, Mestre L, Feliu A, Guaza C, Calzado MA, Munoz E

Effects of EHP-101 on inflammation and remyelination in murine models of Multiple sclerosis

NEUROBIOLOGY OF DISEASE

DOI: 10.1016/j.nbd.2020.104994

Publicaciones 2020

IF: 5,332 Q: 1

Publicaciones 2020

Casares L, Unciti-Broceta JD, Prados ME, Caprioglio D, Mattoteia D, Higgins M, Apendino G, Dinkova-Kostova AT, Munoz E, de la Vega L

Isomeric O-methyl cannabidiolquinones with dual BACH1/NRF2 activity

REDOX BIOLOGY

DOI: 10.1016/j.redox.2020.101689

Publicaciones 2020

IF: 9,986 Q: 1 D: 1

Publicaciones 2020

Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, Schulein-Volk C, Eilers U, Ade CP, Calzado MA, Orian A, Maric HM, Munch C, Rosenfeldt M, Eilers M, Diefenbacher ME

Maintaining protein stability of increment Np63 via USP28 is required by squamous cancer cells

EMBO MOLECULAR MEDICINE

DOI: 10.15252/emmm.201911101

Publicaciones 2020

IF: 8,821 Q: 1 D: 1

Publicaciones 2020

Morrugares R, Correa-Saez A, Moreno R, Garrido-Rodriguez M, Munoz E, de la Vega L, Calzado MA

Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2

CELLULAR AND MOLECULAR LIFE SCIENCES

DOI: 10.1007/s00018-019-03309-9

Publicaciones 2020

IF: 6,496 Q: 1

Publicaciones 2020

Floris I, Rose T, Rojas JAC, Appel K, Roesch C, Lejeune B

Pro-Inflammatory Cytokines at Ultra-Low Dose Exert Anti-Inflammatory Effect In Vitro: A Possible Mode of Action Involving Sub-Micron Particles?

DOSE-RESPONSE

DOI: 10.1177/1559325820961723

Publicaciones 2020

IF: 2,438 Q: 2

Publicaciones 2020

Mattoteia D, Taglialatela-Scafati O, Munoz E, de la Vega L, Caprioglio D, Appendino G

Regiodivergent Synthesis of ortho- and para-Cannabinoquinones

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

DOI: 10.1002/ejoc.202001258

Publicaciones 2020

IF: 2,889 Q: 2

Publicaciones 2020

Palomares B, Ruiz-Pino F, Garrido-Rodriguez M, Prados ME, Sanchez-Garrido MA, Velasco I, Vazquez MJ, Nadal X, Ferreiro-Vera C, Morrugares R, Appendino G, Calzado MA, Tena-Sempere M, Munoz E

Tetrahydrocannabinolic acid A (THCA-A) reduces adiposity and prevents metabolic disease caused by diet-induced obesity

BIOCHEMICAL PHARMACOLOGY

DOI: 10.1016/j.bcp.2019.113693

Publicaciones 2020

IF: 4,96 Q: 1 D: 1

Publicaciones 2020

Caprioglio D, Mattoteia D, Pollastro F, Negri R, Lopatriello A, Chianese G, Minassi A, Collado JA, Munoz E, Taglialatela-Scafati O, Appendino G

The Oxidation of Phytocannabinoids to Cannabinoquinoids

JOURNAL OF NATURAL PRODUCTS

DOI: 10.1021/acs.jnatprod.9b01284

Publicaciones 2020

IF: 3,779 Q: 1

Publicaciones 2020

Correa-Saez A, Jimenez-Izquierdo R, Garrido-Rodriguez M, Morrugares R, Munoz E, Calzado MA

Updating dual-specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2): molecular basis, functions and role in diseases

CELLULAR AND MOLECULAR LIFE SCIENCES

DOI: 10.1007/s00018-020-03556-1

Publicaciones 2020

IF: 6,496 Q: 1

Publicaciones 2019

Morrugares R, Correa-Sáez A, Moreno R, Garrido-Rodríguez M, Muñoz E, de la Vega L, Calzado MA

Phosphorylation-dependent regulation of the NOTCH1 intracellular domain by dual-specificity tyrosine-regulated kinase 2

Cell Mol Life Sci

DOI: 10.1007/s00018-019-03309-9

Publicaciones 2019

IF: 7,014 D: 1

Publicaciones 2019

García-Martín A, Garrido-Rodríguez M, Navarrete C, Caprioglio D, Palomares B, DeMesa J, Rolland A, Appendino G, Muñoz E

Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis

Biochem Pharmacol

DOI: 10.1016/j.bcp.2019.02.029

Publicaciones 2019

IF: 4,825 D: 1

Publicaciones 2019

Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A

LUBAC determines chemotherapy resistance in squamous cell lung cancer

J Exp Med

DOI: 10.1084/jem.20180742

Publicaciones 2019

IF: 10,892 D: 1

Publicaciones 2019

Garrido-Rodríguez M, Ortea I, Calzado MA, Muñoz E, García V

SWATH proteomic profiling of prostate cancer cells identifies NUSAP1 as a potential molecular target for Galiellalactone

J Proteomics

DOI: 10.1016/j.jprot.2018.10.012

Publicaciones 2019

IF: 3, 537 Q: 1

Publicaciones 2019

Aguareles J, Paraíso-Luna J, Palomares B, Bajo-Grañeras R, Navarrete C, Ruiz-Calvo A, García-Rincón D, García-Taboada E, Guzmán M, Muñoz E, Galve-Roperh I

Oral administration of the cannabigerol derivative VCE-003

2 promotes subventricular zone neurogenesis and protects against mutant huntingtin-inducedneurodegeneration

DOI: 10.1186/s40035-019-0148-x

Publicaciones 2019

IF: 5,534 Q: 1

Publicaciones 2018

Ruiz EJ, Diefenbacher ME, Nelson JK, Sancho R, Pucci F, Chakraborty A, Moreno P, Annibaldi A, Liccardi G, Encheva V, Mitter R, Rosenfeldt M, Snijders AP, Meier P, Calzado MA, Behrens A

LUBAC determines chemotherapy resistance in squamous cell lung cancer

J Exp Med

Publicaciones 2018

IF: 10

892 Q: 1 D: 1

Publicaciones 2018

Minassi A, Rogati F, Cruz C, Prados ME, Galera N, Jinenez C, Appendino G, Bellido ML, Calzado MA, Caprioglio D, Munoz E

Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors

JOURNAL OF NATURAL PRODUCTS

Publicaciones 2018

IF: 3,885 Q: 1 D: 1

Publicaciones 2018

Moreno P, Jimenez-Jimenez C, Garrido-Rodriguez M, Calderon-Santiago M, Molina S, Lara-Chica M, Priego-Capote F, Salvatierra A, Munoz E, Calzado MA

Metabolomic profiling of human lung tumor tissues - nucleotide metabolism as a candidate for therapeutic interventions and biomarkers

MOLECULAR ONCOLOGY

Publicaciones 2018

IF: 5,264 Q: 1

Publicaciones 2018

del Rio C, Cantarero I, Palomares B, Gomez-Canas M, Fernandez-Ruiz J, Pavicic C, Garcia-Martin A, Bellido ML, Ortega-Castro R, Perez-Sanchez C, Lopez-Pedrera C, Appendino G, Calzado MA, Munoz E

VCE-004

3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPAR gamma- and CB2 receptor-dependent pathways

Publicaciones 2018

IF: 6,81 Q: 1 D: 1

Publicaciones 2018

Navarrete C, Carrillo-Salinas F, Palomares B, Mecha M, Jimenez-Jimenez C, Mestre L, Feliu A, Bellido ML, Fiebich BL, Appendino G, Calzado MA, Guaza C, Munoz E

Hypoxia mimetic activity of VCE-004

8, a cannabidiol quinone derivative: implications for multiple sclerosis therapy

Publicaciones 2018

IF: 5,193 Q: 1

Publicaciones 2018

Jimenez-Jimenez C, Lara-Chica M, Palomares B, Collado JA, Lopez-Miranda J, Munoz E, Calzado MA

Effect of N-acyl-dopamines on beta cell differentiation and wound healing in diabetic mice

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Publicaciones 2018

IF: 4,651 Q: 1

Publicaciones 2018

Garcia-Martin A, Garrido-Rodriguez M, Navarrete C, del Rio C, Bellido ML, Appendino G, Calzado MA, Munoz E

EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004

8, alleviates bleomycin-induced skin and lung fibrosis

Publicaciones 2018

IF: 4,235 Q: 1

Publicaciones 2018

del Rio C, Millan E, Garcia V, Appendino G, DeMesa J, Munoz E

The endocannabinoid system of the skin

A potential approach for the treatment of skin disorders

Publicaciones 2018

IF: 4,235 Q: 1

Publicaciones 2018

Palomares B, Ruiz-Pino F, Navarrete C, Velasco I, Sanchez-Garrido MA, Jimenez-Jimenez C, Pavicic C, Vazquez MJ, Appendino G, Bellido ML, Calzado MA, Tena-Sempere M, Munoz E

VCE-004

8, A Multitarget Cannabinoquinone, Attenuates Adipogenesis and Prevents Diet-Induced Obesity

Publicaciones 2018

IF: 4,122 Q: 1

Publicaciones 2018

Garcia C, Gomez-Canas M, Burgaz S, Palomares B, Gomez-Galvez Y, Palomo-Garo C, Campo S, Ferrer-Hernandez J, Pavicic C, Navarrete C, Bellido ML, Garcia-Arencibia M, Pazos MR, Munoz E, Fernandez-Ruiz J

Benefits of VCE-003

2, a cannabigerol quinone derivative, against inflammation-driven neuronal deterioration in experimental Parkinson's disease: possible involvement of different binding sites at the PPAR gamma receptor

Publicaciones 2018

IF: 5,193 Q: 1

Publicaciones 2018

Nizet S, Munoz E, Fiebich BL, Abuja PM, Kashofer K, Zatloukal K, Tangermann S, Kenner L, Tschegg C, Nagl D, Scheichl L, Meisslitzer-Ruppitsch C, Freissmuth M, Berger T

Clinoptilolite in Dextran Sulphate Sodium-Induced Murine Colitis: Efficacy and Safety of a Microparticulate Preparation

INFLAMMATORY BOWEL DISEASES

Publicaciones 2018

IF: 4,347 Q: 1

Publicaciones 2018

Rodriguez-Cueto C, Santos-Garcia I, Garcia-Toscano L, Espejo-Porras F, Bellido M, Fernandez-Ruiz J, Munoz E, de Lago E

Neuroprotective effects of the cannabigerol quinone derivative VCE-003

2 in SOD1(G93A) transgenic mice, an experimental model of amyotrophic lateral sclerosis

Publicaciones 2018

IF: 4,235 Q: 1

Publicaciones 2018

Luesma MJ, Cantarero I, Castiella T, Sanchez-Cano AI, Iruzubieta P, Junquera C

Ultrastructural and immunohistochemical study of phenotypic switch in gastrointestinal smooth muscle cells

MICROSCOPY RESEARCH AND TECHNIQUE

Publicaciones 2018

IF: 1,087 Q: 3

Publicaciones 2018

Pollastro F, Caprioglio D, Del Prete D, Rogati F, Minassi A, Taglialatela-Scafati O, Munoz E, Appendino G

Cannabichromene

NATURAL PRODUCT COMMUNICATIONS

Publicaciones 2018

IF: 8,9 Q: 4

Publicaciones 2018

Appel K, Munoz E, Navarrete C, Cruz-Teno C, Biller A, Thiemann E

Immunomodulatory and Inhibitory Effect of Immulina (R), and Immunloges (R) in the Ig-E Mediated Activation of RBL-2H3 Cells

A New Role in Allergic Inflammatory Responses