GC30 GC30 Hepatología Molecular

Montero-Hidalgo AJ, Perez-Gomez JM, Martinez-Fuentes AJ, Gomez-Gomez E, Gahete MD, Jimenez-Vacas JM, Luque RM

Alternative splicing in bladder cancer: potential strategies for cancer diagnosis, prognosis, and treatment

WILEY INTERDISCIPLINARY REVIEWS-RNA

DOI: 10.1002/wrna.1760

Herrera-Martínez AD, Castillo-Peinado LLS, Molina-Puerta MJ, Calanas-Continente A, Membrives A, Castilla J, Cardenosa MC, Casado-Díaz A, Gálvez-Moreno MA, Gahete MD, Gómez JMQ, Bouillon R, Priego-Capote F, Luque RM

Bariatric surgery and calcifediol treatment, Gordian knot of severe-obesity-related comorbidities treatment

FRONTIERS IN ENDOCRINOLOGY

DOI: 10.3389/fendo.2023.1243906

Arias-de la Rosa I, Ruiz-Ponce M, Cuesta-López L, Pérez-Sánchez C, Leiva-Cepas F, Gahete M, Navarro P, Ortega R, Cordoba J, Pérez-Pampin E, González A, Lucendo AJ, Collantes-Estévez E, López-Pedrera C, Escudero-Contreras A, Barbarroja N

Clinical features and immune mechanisms directly linked to the altered liver function in patients with rheumatoid arthritis

EUROPEAN JOURNAL OF INTERNAL MEDICINE

DOI: 10.1016/j.ejim.2023.08.002

Ruiz-Ponce M, Cuesta-López L, López-Montilla MD, Pérez-Sánchez C, Ortiz-Buitrago P, Barranco A, Gahete MD, Herman-Sánchez N, Lucendo AJ, Navarro P, López-Pedrera C, Escudero-Contreras A, Collantes-Estévez E, López-Medina C, Arias-de la Rosa I, Barbarroja N

Decoding clinical and molecular pathways of liver dysfunction in Psoriatic Arthritis: Impact of cumulative methotrexate doses

BIOMEDICINE & PHARMACOTHERAPY

DOI: 10.1016/j.biopha.2023.115779

Pérez-Gómez JM, Porcel-Pastrana F, De La Luz-Borrero M, Montero-Hidalgo AJ, Gómez-Gómez E, Herrera-Martínez AD, Guzmán-Ruiz R, Malagón MM, Gahete MD, Luque RM

LRP10, PGK1 and RPLP0: Best Reference Genes in Periprostatic Adipose Tissue under Obesity and Prostate Cancer Conditions

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DOI: 10.3390/ijms242015140

Fuentes-Fayos AC, G-Garcia ME, Perez-Gomez JM, Montero-Hidalgo AJ, Martin-Colom J, Doval-Rosa C, Blanco-Acevedo C, Torres E, Toledano-Delgado A, Sanchez-Sanchez R, Peralbo-Santaella E, Ortega-Salas RM, Jimenez-Vacas JM, Tena-Sempere M, Lopez M, Castano JP, Gahete MD, Solivera J, Luque RM

Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence

EBIOMEDICINE

DOI: 10.1016/j.ebiom.2023.104484

Lopez-Canovas JL, Herman-Sanchez N, del Rio-Moreno M, Fuentes-Fayos AC, Lara-Lopez A, Sanchez-Frias ME, Amado V, Ciria R, Briceno J, de la Mata M, Castano JP, Rodriguez-Peralvarez M, Luque RM, Gahete MD

PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing

EXPERIMENTAL AND MOLECULAR MEDICINE

DOI: 10.1038/s12276-022-00917-7

Pedraza-Arevalo S, Alors-Perez E, Blazquez-Encinas R, Herrera-Martinez AD, Jimenz-Vacas JM, Fuentes-Fayos AC, Reyes O, Ventura S, Sanchez-Sanchez R, Ortega-Salas R, Serrano-Blanch R, Galvez-Moreno MA, Gahete MD, Ibanez-Costa A, Luque RM, Castano JP

Spliceosomic dysregulation unveils NOVA1 as a candidate actionable therapeutic target in pancreatic neuroendocrine tumors

TRANSLATIONAL RESEARCH

DOI: 10.1016/j.trsl.2022.07.005

Jimenez-Vacas JM, Montero-Hidalgo AJ, Gomez-Gomez E, Saez-Martinez P, Fuentes-Fayos AC, Closa A, Gonzalez-Serrano T, Martinez-Lopez A, Sanchez-Sanchez R, Lopez-Casas PP, Sarmento-Cabral A, Olmos D, Eyras E, Castano JP, Gahete MD, Luque RM

Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes

TRANSLATIONAL RESEARCH

DOI: 10.1016/j.trsl.2022.08.016

López-Cánovas JL, Hermán-Sánchez N, Del Rio-Moreno M, Fuentes-Fayos AC, Lara-López A, Sánchez-Frias ME, Amado V, Ciria R, Briceño J, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD

PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing

Exp Mol Med

DOI: 10.1038/s12276-022-00917-7

IF: 12,172 Q: 1 D: 1

López-Cánovas JL, Hermán-Sánchez N, Moreno-Montilla MT, Del Rio-Moreno M, Alors-Perez E, Sánchez-Frias ME, Amado V, Ciria R, Briceño J, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD

Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing

Clin Transl Med

DOI: 10.1002/ctm2.1102

IF: 8,554 Q: 1

Herrera-Martínez AD, Herrero-Aguayo V, Pérez-Gómez JM, Gahete MD, Luque RM

Inflammasomes: Cause or consequence of obesity-associated comorbidities in humans

Obesity (Silver Spring)

DOI: 10.1002/oby.23581

IF: 9,298 Q: 1 D:1